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Comprised of Lake Marion and Lake Moultrie, the Santee Cooper Lakes feature 160,000-acres of angler paradise. With some of the best fishing in South Carolina, Santee Cooper is a world-class fishery with a jaw dropping drowned forest known for a wide range of freshwater species. Known for its big fish, it’s important to come to Santee Cooper prepared for battle. Flipping creature baits or throwing spinnerbaits around the cypress knees have always been popular techniques at Santee Cooper. Our Berkley scientists have collaborated with local anglers and guides to determine which baits draw the most bites each season so you can have the best possible chance of catching a bass of a lifetime.